Hypothalamo-pituitary-thyroid axis function during cardiopulmonary bypass

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Thyroid-pituitary response to cardiopulmonary bypass.

The effects of open heart surgery on various parameters of thyroid-pituitary function were studied in 11 patients. The pattern of hormonal changes was variable. T4 concentration increased during anaesthesia and bypass, following which it returned to normal once haemodynamic stability had been regained. The pattern of change in T3 concentration did not follow consistently that of T4 and the prop...

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The hypothalamo-pituitary–gonadal axis

This review provides an outline of how our understanding of the neuroendocrine control of the hypothalamo-pituitary–gonadal axis has evolved since the publication of Geoffrey Harris’ renowned monograph in 1955. Particular attention is directed to the neurobiology underlying pulsatile GnRH release from the hypothalamus, the neuroendocrine control of ovarian cycles, puberty and seasonality of gon...

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Thyroid function during coronary surgery with and without cardiopulmonary bypass.

OBJECTIVE Cardiopulmonary bypass (CPB) is associated with thyroid hormone changes consistent with euthyroid sick syndrome. Similar changes have been observed after general surgical operations. Thyroid hormone changes and their association with global oxygen consumption were studied in low-risk patients undergoing coronary artery bypass grafting (CABG) with and without CPB. METHODS Fifty-two p...

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The Pituitary-Thyroid Axis in Acromegaly

The pituitary-Thyroid axis of 12 Acromegalic patients was evaluated by measurement of the concentration (Total and free of thyroxine T4, T3 and revers T3 (rT3) and TSH, GH and prolactin before and after in stimulation with TRH. Using an ultra­sensitive method of TSH measurement (IRMA) basal serum TSH levels of patients (0.76, 0.07-l.90mlU/L) were found slightly but significantly (P < 0.01), low...

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ژورنال

عنوان ژورنال: The Journal of Thoracic and Cardiovascular Surgery

سال: 1978

ISSN: 0022-5223

DOI: 10.1016/s0022-5223(19)41266-x